Rolf Sprengel Selected Research

AMPA Receptors (AMPA Receptor)

11/2021	Deletion of AMPA receptor GluA1 subunit gene (Gria1) causes circadian rhythm disruption and aberrant responses to environmental cues.
1/2021	The GluA1 AMPAR subunit is necessary for hedonic responding but not hedonic value in female mice.
1/2019	Attenuation of Novelty-Induced Hyperactivity of Gria1-/- Mice by Cannabidiol and Hippocampal Inhibitory Chemogenetics.
1/2018	Absent sleep EEG spindle activity in GluA1 (Gria1) knockout mice: relevance to neuropsychiatric disorders.
1/2017	GluA1 AMPAR subunit deletion reduces the hedonic response to sucrose but leaves satiety and conditioned responses intact.
10/2014	Impact of adolescent GluA1 AMPA receptor ablation in forebrain excitatory neurons on behavioural correlates of mood disorders.
4/2014	Phenotype of mice with inducible ablation of GluA1 AMPA receptors during late adolescence: relevance for mental disorders.
4/2011	Peripheral calcium-permeable AMPA receptors regulate chronic inflammatory pain in mice.
1/2011	Excessive novelty-induced c-Fos expression and altered neurogenesis in the hippocampus of GluA1 knockout mice.
1/2011	The puzzle box as a simple and efficient behavioral test for exploring impairments of general cognition and executive functions in mouse models of schizophrenia.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Rolf Sprengel Research Topics

Disease

12	Schizophrenia (Dementia Praecox) 11/2021 - 03/2010
5	Psychotic Disorders (Schizoaffective Disorder) 01/2021 - 03/2010
5	Pain (Aches) 03/2016 - 11/2004
4	Seizures (Absence Seizure) 02/2021 - 11/2004
4	Mental Disorders (Mental Disorder) 01/2021 - 01/2011
3	Intellectual Disability (Idiocy) 01/2021 - 06/2010
3	Mania (Manias) 01/2019 - 01/2011
2	Body Weight (Weight, Body) 01/2022 - 11/2011
2	Hypothermia 01/2020 - 08/2014
2	Mood Disorders (Mood Disorder) 01/2015 - 10/2014
2	Neurodegenerative Diseases (Neurodegenerative Disease) 03/2014 - 06/2013
2	Inflammation (Inflammations) 08/2009 - 11/2008
1	Neurologic Manifestations (Neurological Manifestations) 01/2021
1	Partial Epilepsies (Epilepsy, Partial) 01/2021
1	Anhedonia 01/2021
1	Autism Spectrum Disorder 12/2020
1	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 01/2019
1	Neuroblastoma 01/2018
1	Major Depressive Disorder (Major Depressive Disorders) 01/2018
1	Dehydration (Water Stress) 01/2015
1	Alzheimer Disease (Alzheimer's Disease) 03/2014
1	Immune System Diseases (Immune Disorders) 03/2014
1	Genetic Translocation (Chromosomal Translocation) 12/2013
1	Opioid-Related Disorders (Opiate Addiction) 11/2012
1	Substance Withdrawal Syndrome (Withdrawal Symptoms) 11/2012
1	Morphine Dependence 11/2012
1	Obesity 11/2011
1	AIDS-Related Complex (ARC) 09/2011
1	Virus Diseases (Viral Diseases) 02/2009
1	Generalized Epilepsy 09/2008
1	Absence Epilepsy (Childhood Absence Epilepsy) 10/2007
1	Febrile Seizures (Febrile Seizure) 10/2007
1	Leukemia 09/2006
1	Hyperalgesia 11/2004

Drug/Important Bio-Agent (IBA)

13	AMPA Receptors (AMPA Receptor)IBA 11/2021 - 11/2004
8	Glutamic Acid (Glutamate)FDA Link 11/2021 - 03/2010
7	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 02/2021 - 03/2010
4	alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA 11/2019 - 11/2004
3	AcidsIBA 11/2021 - 01/2011
3	Proteins (Proteins, Gene)FDA Link 11/2019 - 12/2013
3	Glutamate Receptors (Glutamate Receptor)IBA 01/2017 - 11/2004
2	CorticosteroneIBA 01/2022 - 08/2014
2	Pharmaceutical PreparationsIBA 12/2020 - 11/2012
2	Kainic Acid (Kainate)IBA 11/2018 - 06/2013
2	CalciumIBA 04/2011 - 11/2008
2	glutamate receptor type BIBA 11/2004 - 11/2004
1	ParvalbuminsIBA 01/2021
1	Neuregulin-1 (Neuregulin 1)IBA 01/2021
1	Tamoxifen FDA LinkGeneric 01/2021
1	TARPIBA 11/2019
1	Gonadal Steroid Hormones (Sex Hormones)IBA 01/2018
1	Dihydrotestosterone (Androstanolone)IBA 01/2018
1	eglumetadIBA 01/2017
1	Oxytocin (Pitocin)FDA LinkGeneric 03/2016
1	Ketamine FDA LinkGeneric 01/2015
1	tert-Butyl Alcohol (tert-Butanol)IBA 01/2015
1	1-Propanol (Propanol)IBA 01/2015
1	Antidepressive Agents (Antidepressants)IBA 01/2015
1	SolutionsIBA 01/2015
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 08/2014
1	Peptides (Polypeptides)IBA 03/2014
1	Immunosuppressive Agents (Immunosuppressants)IBA 03/2014
1	Memantine (Namenda)FDA Link 03/2014
1	Core Binding Factors (Core-Binding Factor)IBA 12/2013
1	Ro 25-6981IBA 08/2013
1	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 08/2013
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 11/2012
1	Morphine (MS Contin)FDA LinkGeneric 11/2012
1	Neuropeptide YIBA 11/2011
1	LeptinIBA 11/2011
1	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 09/2011
1	activity regulated cytoskeletal-associated proteinIBA 09/2011
1	Dopamine D2 Receptors (Dopamine D2 Receptor)IBA 01/2011
1	Dizocilpine Maleate (Dizocilpine)IBA 01/2011
1	Nonsense Codon (Nonsense Mutation)IBA 06/2010
1	DNA (Deoxyribonucleic Acid)IBA 06/2010
1	Antipsychotic Agents (Antipsychotics)IBA 03/2010
1	PlasticsIBA 08/2009
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 08/2009
1	AntigensIBA 02/2009
1	gamma-Aminobutyric Acid (GABA)IBA 09/2008
1	Ethosuximide (Zarontin)FDA LinkGeneric 10/2007
1	GABA-A Receptors (GABA(A) Receptor)IBA 10/2007
1	Basic Helix-Loop-Helix Transcription FactorsIBA 09/2006

Therapy/Procedure

2	Therapeutics 01/2013 - 03/2010
1	Anesthesia 01/2020
1	Analgesia 03/2016
1	Aftercare (After-Treatment) 08/2013